Review of actinide decorporation with chelating agents

A Mini-Review on Iron Chelating Agents as a Promising Therapeutic Target in Treatment of Leishmaniasis

There is a high prevalence of infections caused by Leishmania parasites and increasing rate of drug resistance. Lack of successful treatment with existing drugs calls for new therapeutic approaches. The main strategy in treatment of leishmaniasis is creating apoptosis and eliminating different forms of the parasite. So far, numerous drugs with specific mechanisms including 14-α-demethylase enzy...

Critical Review Environmental Chemistry of Aminopolycarboxylate Chelating Agents

Aminopolycarboxylate chelating agents are under scrutiny due to their influence on metal availability and mobility and in particular due to their persistence in the environment. In this review chelate adsorption, metal-mobilization, metalexchange, mineral dissolution, reactive transport, photodegradation, and chemical degradation are all shown to be substantially affected by the chelated metal ...

Chromatographic Separations with Selected Supported Chelating Agents

Design of therapeutic chelating agents.

The successful design of orally active non-toxic selective metal chelators is a much sought-after goal. In order to identify an ideal chelator for clinical use, a range of specifications must be considered, such as metal selectivity and affinity, kinetic stability of the complex, bioavailability and toxicity. In this overview the comparative properties of ligands capable of endowing complexes w...

Actinide-specific Sequestering Agents and Decontamination Applications